US River Cruise Destinations

From the Deep South to the Pacific Northwest, America’s rivers offer astonishing variety. Here are the routes worth knowing.

The Lower Mississippi

New Orleans to Memphis — antebellum mansions, Civil War history, Delta blues and Southern cuisine, aboard grand paddlewheelers.

The Upper Mississippi

St. Louis to St. Paul — river bluffs, small Midwestern towns, Mark Twain country and glorious fall color.

The Columbia & Snake

The Pacific Northwest — Lewis & Clark’s route, Multnomah Falls, Columbia Gorge wine country and Mount Hood views.

The Ohio, Tennessee & Cumberland

Nashville to the heartland — music, history and some of America’s finest autumn foliage.

The Hudson & Northeast

New York City, West Point, Hudson Valley estates and New England’s coastal rivers and fall colors.

Heading to New Orleans for a paddlewheeler or New York for the Hudson? Compare hotels in New Orleans and New York City hotels before you fly.

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