US River Cruise Destinations
From the Deep South to the Pacific Northwest, America’s rivers offer astonishing variety. Here are the routes worth knowing.

The Lower Mississippi
New Orleans to Memphis — antebellum mansions, Civil War history, Delta blues and Southern cuisine, aboard grand paddlewheelers.
The Upper Mississippi
St. Louis to St. Paul — river bluffs, small Midwestern towns, Mark Twain country and glorious fall color.
The Columbia & Snake
The Pacific Northwest — Lewis & Clark’s route, Multnomah Falls, Columbia Gorge wine country and Mount Hood views.
The Ohio, Tennessee & Cumberland
Nashville to the heartland — music, history and some of America’s finest autumn foliage.
The Hudson & Northeast
New York City, West Point, Hudson Valley estates and New England’s coastal rivers and fall colors.
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